As the years go by, our skin starts to look worse than it used to.

Due to natural processes, depletion of collagen and environmental factors, wrinkles and other unsightly things on our skin can make us look old and tired – sometimes older than we really are.

Collagen provides the support matrix/mattress underpinning healthy skin and is a key determinant to the preservation of skin firmness and elasticity [1,2]. Type I is the main collagen found in skin, representing 80%-90% of skin collagen.

Collagen is key for preservation of skin firmness and elasticity, and making our skin look youthful. With age, the ability to replenish collagen naturally decreases by about 1.0%-1.5% per year.

What Are The Benefits Of At-Home Microneedling?

Stimulates collagen production

Reduces the appearance of wrinkles and fine lines [1]

Elevates the overall texture of your skin [1]

Improves skin texture

Helps fade scars and hyperpigmentation

Enhances topical products penetration [2]

Microneedle Stamp

✔  Flat head on which the needles rest, and instead of rolling the tool across the area to be treated, you simply stamp it.

✔  More effective than chemical peels and microneedle rollers.
 
✔  Cause less trauma to the epidermis, as stamping does not “pick up” the epidermis of the skin as a microneedle roller does.

 
✔  Reduced level of pain and discomfort.

Microneedle Roller
(or Dermaroller)

  • Barrel head full of small needles that glide over skin.

  • Covers larger area

  • Faster treatment.

  • No control over depth penetration

  • Needles often need to be disinfected if not single use

  • Rolling technique can cause micro tears

  • Uncontrolled injury to skin can take longer to heal 

Microneedle Stamp

  • Flat head head full of small needles that stamp into the skin.

  • Covers smaller areas

  • Cause less trauma to the epidermis, as stamping does not “pick up” the epidermis of the skin as a microneedle roller does.

  • Reduced level of pain and discomfort.

Best Overall

by Qure Skincare

872 Reviews

Qure All-In-One Face Serum 

Contains active & clinically-proven ingredients that brightens skin tone, lightens dark spots and reduces appearance of fine lines.  

2,367 people chose this today

Before $85.00  NOW $59.00

   ★ 

CLICK TO SHOP NOW

High concentration of Argireline Peptides
that leading Dermatologists recommend as a topical option to mimic Botox.

Affordable price compared to other serums with peptides and retinol formula.

Fast shipping to USA, Canada, United Kingdom and Australia.

Suitable for all skin types.

© 2022 Skincare-productreviews.com. All Rights Reserved. 

Trademarks utilized on our website belong to their respective owners and no implied or  endorsement of our website or services is intended.

Typically there are two categories when considering an at-home microneedling device. The shape and design of the tool varies. 

Different Types of At-Home Microneedling Devices

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Best Overall

Click To Shop Now

by Qure Skincare

872 Reviews

Qure Micro-Infusion System

Quick, easy and convenient skin booster treatment. Infuse your skin with instant-glow ingredients to feel confident at any age.  

Stimulates collagen whilst infusing active ingredients directly into your skin for immediately visible results.

No downtime, virtually painless and performed safely in the comfort of your home. 

Used in clinics by clinical research & dermatologist-approved. 

2,367 people chose this today

48% OFF + FREE Shipping

The Best Rated Microneedling At-Home Facial For Rejuvenating Skin

If you look in the mirror and see something you'd like to improve about your skin — whether it's minimizing scars, reducing fine lines, evening out skin tone, or simply achieving a more radiant glow — microneedling could be the answer.

It involves the use of ultra-fine microneedles being passed over the face. The needles create micro-injuries on the skin, which in turn sends collagen and elastin production into overdrive to compensate as it heals—leaving your complexion tighter and plumper than it was beforehand. [1] 

Plus, when used in conjunction with a serum (as it should be), it can significantly boost ingredient absorption, and therefore boost results. 

As uncomfortable as it sounds, the results can be transformative.

For a more intense, in-office treatment, many dermatologists use an electronic microneedling device that punctures the skin. These treatments often have immediate and dramatic results but can also have side effects like pain and bleeding, tend to be expensive and require downtime.

Though the practice of microneedling started in dermatologists' offices, now, needling treatments are widely available for affordable and convenient home use. You get great results with regular maintenance, and it requires a much lower pain threshold, too.

Hundreds are skipping the “in person” dermatologist visits for something a little more accessible, affordable, and requires no commute time.

Based on research and guidelines from dermatologists and the top-rated devices on the market, we outlined the best microneedling devices you can safely use at home to treat various concerns, assessing their ease of use, safety, comfort levels and results.

What Are The Benefits Of At-Home Microneedling?

Retinol (Vitamin A)

is a key ingredient when it comes to improving the signs of aging, it works to increase cell turnover, build collagen, improve discoloration, [and] treat wrinkles. It essentially teaches aging skin cells how to behave like younger, healthier cells by encouraging them to turnover more rapidly. So if a product contains retinol, you can expect to see smoother, brighter, firmer skin.

Stimulates collagen production

Reduces the appearance of wrinkles and fine lines [1]

Elevates the overall texture of your skin [1]

Improves skin texture

Helps fade scars and hyperpigmentation

Enhances topical products penetration [2]

Different Types of At-Home Microneedling Devices

Typically there are two categories when considering an at-home microneedling device. The shape and design of the tool varies. 

Microneedle Stamp

  • Flat head head full of small needles that stamp into the skin.

  • Covers smaller areas

  • Cause less trauma to the epidermis, as stamping does not “pick up” the epidermis of the skin as a microneedle roller does.

  • Reduced level of pain and discomfort.

Microneedle Roller
(or Dermaroller)

  • Barrel head full of small needles that glide over skin.

  • Covers larger area

  • Faster treatment.

  • No control over depth penetration

  • Needles often need to be disinfected if not single use

  • Rolling technique can cause micro tears

  • Uncontrolled injury to skin can take longer to heal 

AnteAGE Home Microneedling Intro Kit

TOTAL RANKING

316 votes

7.9/10

WHAT WE LIKE

Paraben-free, FD&C dye-free, Sulfate-free

Can be used post-procedure to initiate healing response

This includes an easy-to-apply serum

WHAT WE DON'T LIKE

Pricey

Growth factors and cytokines derived from laboratory culture of human bone marrow stem cells

Targets fine lines and minimizes pores

Hasn't been able to perform well enough to merit a spot in any roundups of Derma Rollers produced by sources who do their own high-quality, hands-on testing.

VIEW ON ANTEAGE.COM

Quality

Ease of Use

Safety

Result

7.8/10

8.0/10

8.3/10

7.8/10

7.6/10

Overall Customer Satisfaction

Hundreds are skipping the “in person” dermatologist visits for something a little more accessible, affordable, and requires no commute time.

Based on research and guidelines from dermatologists and the top-rated devices on the market, we outlined the best microneedling devices you can safely use at home to treat various concerns, assessing their ease of use, safety, comfort levels and results.

Hundreds are skipping the “in person” dermatologist visits for something a little more accessible, affordable, and requires no commute time.

Based on research and guidelines from dermatologists and the top-rated devices on the market, we outlined the best microneedling devices you can safely use at home to treat various concerns, assessing their ease of use, safety, comfort levels and results.

MUST WATCH VIDEO!

Doctorly Dr Shah & Dr Maxfield
      Certified Dermatologists 

Tested & Recommended By World-Leading Dermatologists

Tested & Recommended By World-Leading Dermatologists 

MUST WATCH VIDEO!

Doctorly Dr Shah & Dr Maxfield
      Certified Dermatologists 

Tested and Approved by Top Dermatologists

Dr Maxfield, MD (Doctorly)
Certified Dermatologist

"In terms of safety, the micro stamping devices, this [Qure's Micro-Infusion] is great..."

MUST WATCH VIDEO!

Doctorly Dr Shah & Dr Maxfield
      Certified Dermatologists 

Tested and Approved by Top Dermatologists

Dr Shah, MD (Doctorly)     
Certified Dermatologist

"This will definitely work and there have been studies to show that this will definitely work to help your products penetrate better"

Dr Maxfield,MD (Doctorly)     
Certified Dermatologist

"In terms of safety, the micro stamping devices, this [Qure's Micro-Infusion] is great..."

Tested & Recommended By World-Leading Dermatologists 

"This will definitely work and there have been studies to show that this will definitely work to help your products penetrate better"

Dr Shah, MD (Doctorly)       Certified Dermatologist

"In terms of safety, the micro stamping devices, this [Qure's Micro-Infusion] is great..."

Dr Maxfield, MD (Doctorly)       Certified Dermatologist

Is MICRONEEDLING Worth the Hype? Doctorly Explains

461K views  •  3 months ago

Is MICRONEEDLING Worth the Hype? Doctorly Explains

461K views  •  2 months ago

Tested & Recommended By World-Leading Dermatologists 

"This will definitely work and there have been studies to show that this will definitely work to help your products penetrate better"

Dr Shah, MD (Doctorly)
Certified Dermatologist

Dr Maxfield, MD (Doctorly)
Certified Dermatologist

"In terms of safety, the micro stamping devices, this [Qure's Micro-Infusion] is great..."

Is MICRONEEDLING Worth the Hype? Doctorly Explains

461K views  •  2 months ago

"This will definitely work and there have been studies to show that this will definitely work to help your products penetrate better"

Dr Shah, MD (Doctorly)
Certified Dermatologist

"In terms of safety, the micro stamping devices, this [Qure's Micro-Infusion] is great..."

Dr Maxfield, MD (Doctorly)
Certified Dermatologist

Click here to watch review
Click here to watch

© 2023 Skincare-productreviews.com. All Rights Reserved. 

Trademarks utilized on our website belong to their respective owners and no implied or endorsement of our website or services is intended.

The Final Word Qure Micro-Infusion System

Qure’s Micro-Infusion 2-in-1 system is leading the industry in innovation and results. You get to choose between clinically-formulated serums tailored to your specific skin concerns.


Qure Skincare uses 24K gold clinical-grade needles because of their superior cleanliness. On top of that, the needles are thinner than human hair so you hardly feel them. These special needles create “microchannels” that help deliver your serum where they can do the most good.


The result is a 300% increase in absorption for an instant lift in your appearance. No other product came close to Qure’s Micro-Infusion results, not even the more expensive options.


It turns out that I wasn’t the first to discover Qure either, based on their massive following. To date they have over 30,000 diehard fans who swear by their results. Which is both good news and bad news.


It’s good news because it’s clear that Qure’s Micro-Infusion system is becoming the leading solution for thousands. But bad news because as they grow in popularity, Qure is having trouble keeping enough product in stock.


As of this review, Qure is offering up to a 43% discount and a 90-day money back guarantee. So if you’re looking to tame fine lines, wrinkles, scars or uneven pigmentation then Qure’s Micro-Infusion system is the obvious choice for you.


Based on what I, and thousands of other people have discovered, Qure offers the best results for your investment.

Countless patients have come to me over the years complaining of crow’s feet, dull skin, fine lines, and more. Many of them are convinced that their only hope for smooth, youthful-looking skin is to go under the needle.

However, one of the best ways to combat signs of aging is by using anti-aging skincare. This is one of the most effective, non-invasive ways to address signs of aging like wrinkles and fine lines, hyperpigmentation, hydration, sagging skin and more.

But the biggest problem for my patients is that the market is absolutely flooded with competition, and the cosmetics industry is not only hugely profitable, but growing.

Hundreds and hundreds of different products all claiming to do the same thing can't be equally worth your time or money, so 
how do you figure out which one to buy?

With so many products on the market, it seems an impossible task to sort the good from the bad, the nice-smelling but useless serums from the effective “holy grail” skincare.

Over the years I have had the opportunity to test hundreds of anti-aging serums on both myself and my patients. And there have been a few standout winners that I keep coming back to.

Today, I would like to share with you my top 5 serums for smooth, youthful-looking skin to enhance the natural beauty of your face…

The Final Word Qure Micro-Infusion System

Qure’s Micro-Infusion 2-in-1 system is leading the industry in innovation and results. You get to choose between clinically-formulated serums tailored to your specific skin concerns.


Qure Skincare uses 24K gold clinical-grade needles because of their superior cleanliness. On top of that, the needles are thinner than human hair so you hardly feel them. These special needles create “microchannels” that help deliver your serum where they can do the most good.


The result is a 300% increase in absorption for an instant lift in your appearance. No other product came close to Qure’s Micro-Infusion results, not even the more expensive options.


It turns out that I wasn’t the first to discover Qure either, based on their massive following. To date they have over 30,000 diehard fans who swear by their results. Which is both good news and bad news.


It’s good news because it’s clear that Qure’s Micro-Infusion system is becoming the leading solution for thousands. But bad news because as they grow in popularity, Qure is having trouble keeping enough product in stock.


As of this review, Qure is offering up to a 43% discount and a 90-day money back guarantee. So if you’re looking to tame fine lines, wrinkles, scars or uneven pigmentation then Qure’s Micro-Infusion system is the obvious choice for you.


Based on what I, and thousands of other people have discovered, Qure offers the best results for your investment.

Don't choose your Skincare Routine before reading this

ADVERTORIAL

SKIN

MAKEUP

HAIR

STYLE

NEWS

WHAT TO BUY

HEALTH & WELLNESS

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As A Dermatologist, I’ve Tested Hundreds of Anti-Aging Serums - Here Are 5 That Actually Work!

Latest Reviews

Best Ingredients 

Comparisons

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By: Dr. Anna Nichols, MD  

Board Certified Dermatologist, Harvard Graduate

Advertiser Disclosure

Best Microneedling At-Home Device 2023

Latest update: June 16th, 2023

SKIN        FACE CARE        EYE CARE

We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation. Learn more.

Latest Reviews    |    Safety & Ease Of Use    |    Comparisons    |    Costs & More

Best Microneedling At-Home Device 2023

Qure Micro-Infusion System

Honestly, this skin stamping system blew me away.

It’s unique because it delivers targeted serums through hollow-tip needles as you stamp your skin! I think it’s brilliant. Qure’s studies say that this system allows a 300% boost in serum absorption.

From what I’ve seen, nobody else has a serum delivery system like Qure’s. I’ve had clients use this system, and they get both immediately-visible results and long-term improvement in their skin conditions.

CHECK OUT QURE’S MICRO-INFUSION SYSTEM

I also love this system because it has a much lower chance of irritating or infecting your skin.

Other rolling or stamping devices can get damaged needles if they’re stored improperly or used when dull. All it takes is one damaged needle to wreak havoc on your skin. Plus most needling devices need to be sterilized each time in order to prevent skin infections.

This Qure system uses disposable needle heads. They’re much easier to store without damaging, they won’t get dull from overuse, and they don’t require the sterilization that reusable products need. There’s just less room for error.

I also want to mention that this company offers multiple serums, so you can customize your skincare goals. And they say that this needle-infusion treatment only takes 5 minutes for your whole face.

Overall, I’ve seen people get glowing results from this product, and as a medical professional I prefer the disposable needle heads for maximum impact and a much lower chance of skin damage. So it earns the top spot in my at-home needling lineup.

1

    4.9

Tested & Recommended By World-Leading Dermatologists

"This will definitely work and there have been studies to show that this will definitely work to help your products penetrate better"

Dr Shah, MD (Doctorly)        Certified Dermatologist

"In terms of safety, the micro stamping devices, this [Qure's Micro-Infusion] is great..."

Dr Maxfield, MD (Doctorly)         Certified Dermatologist

“I personally think my products absorbed better, my skin looks a bit
brighter and that larger acne scar on my right cheek has started to fade after just TWO treatments!” 

Dr Mona Patel, MD         Certified Dermatologist

Check Out Bio Serum Firm Serum

5.  Neocutis Bio Serum Firm 

C Rating 

Tested & Recommended By World-Leading Dermatologists

"This will definitely work and there have been studies to show that this will definitely work to help your products penetrate better"

Dr Shah, MD (Doctorly)        Certified Dermatologist

"In terms of safety, the micro stamping devices, this [Qure's Micro-Infusion] is great..."

Dr Maxfield, MD (Doctorly)         Certified Dermatologist

“I personally think my products absorbed better, my skin looks a bit
brighter and that larger acne scar on my right cheek has started to fade after just TWO treatments!” 

Dr Mona Patel, MD         Certified Dermatologist

✅   PROS

  • Fades and prevents dark spots

  • Smooths fine lines and wrinkles

  • Contains great anti-aging  ingredients

  • Well priced & affordable

  • Fragrance-free & vegan 

❌   CONS 

  • Not available in brick and mortar shops

  • Often sold out due to popularity 

✅   PROS

  • Keeps skin hydrated

  • Softens fine lines 

  • Won’t clog pores

❌   CONS 

  • Runs out quickly 

  • Pricey for what it is

  • Not enough active ingredients 

Skin type: Dry, sensitive
Benefits: Locks in hydration and softens skin  
Key ingredients: Sodium hyaluronate (a form of hyaluronic acid) 
Size: 1 oz / 30 mL 

The Bottom Line

An intensive rejuvenating serum treatment features high concentration of proven, anti-aging ingredients Growth Factors and Peptides.


A little bit goes a long way as it has a thick, creamy consistency. If dark circles and
hyperpigmentation are getting you down, this cream is a great choice.
help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine.

On some patient's skin types, the product takes longer to absorb, which sometimes resulted in pilling. But it still produced great results. 

¹Ablon, Glynis. “Phototherapy with Light Emitting Diodes: Treating a Broad Range of Medical and Aesthetic Conditions in Dermatology.” The Journal of Clinical and Aesthetic Dermatology, Matrix Medical Communications, Feb. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC5843358/.

Lim SH, Sun Y, Thiruvallur madanagopal T, Rosa V, Kang L. Enhanced skin permeation of anti-wrinkle peptides via molecular modification. Sci Rep. 2018;8(1):1596. doi:10.1038/s41598-017-18454-z, https://www.nature.com/articles/s41598-017-18454-z

Mukherjee S, Date A, Patravale V, Korting HC, Roeder A, Weindl G. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clin Interv Aging. 2006;1(4):327-348. doi:10.2147/ciia.2006.1.4.327

CITATIONS

Click to Shop Now

by Qure Skincare

872 Reviews

All-In-One Face Serum

Contains clinically-proven ingredients that brightens skin tone, fade pigmentation and reduces appearance of  fine lines. 

Affordable price compared to other products with peptides and retinol.

Fast shipping to USA, Canada, United Kingdom and Australia.

Suitable for all skin types.

Recommended by leading Dermatologists 

2,367 people chose this today

Before $85.00  NOW $59.00 

Best Overall Serum

As A Dermatologist, I’ve Tested Hundreds of Anti-Aging Serums - Here Are 5 That Actually Work!

Latest Reviews

Best Ingredients 

Comparisons

Costs & More

By: Dr. Alexandra Zeitany, MD  

Board Certified Dermatologist

Advertiser Disclosure

As A Dermatologist, I’ve Tested Hundreds of Anti-Aging Serums - Here Are 5 That Actually Work! 

Latest update:  March 5th, 2024 |  10,818 Views 

SKIN        FACE CARE        EYE CARE

We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation. Learn more.

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MAKEUP

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NAILS

STYLE

NEWS

WHAT TO BUY

HEALTH & WELLNESS

ABOUT US

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As A Dermatologist, I’ve Tested Hundreds of Anti-Aging Serums - Here Are 5 That Actually Work! 

Latest update: May 9th, 2022

Advertiser Disclosure

Latest Reviews

Best Ingredients

Comparisons

Costs & More

By: Dr. Alexandra Zeitany, MD

Board Certified Dermatologist, Harvard Graduate

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⧗ Latest update: May 24th, 2022
👁 8,818 Views

Latest update:  March 5th, 2024 |  10,818 Views 

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SKIN    ■    FACE CARE    ■    EYE CARE

Don't choose your Skincare Routine before reading this

Neocutis Bio Serum Firm 

5.

C Rating 

Tested & Recommended By World-Leading Dermatologists

This will definitely work
and there have been
studies to show that this will definitely work to help your products penetrate better"

Dr Shah, MD (Doctorly)
Certified Dermatologist

"In terms of safety, the micro stamping devices, this [Qure's Micro-Infusion] is great..."

Dr Maxfield, MD (Doctorly)
Certified Dermatologist

“I personally think my
products absorbed better, my skin looks a bit brighter and that larger acne scar on my right cheek has started to fade after just TWO treatments!” 

Dr Mona Patel, MD
Certified Dermatologist

The Bottom Line

An intensive rejuvenating serum treatment features high concentration of proven, anti-aging ingredients Growth Factors and Peptides.


A little bit goes a long way as it has a thick, creamy consistency. If dark circles and

hyperpigmentation are getting you down, this cream is a great choice.
help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine.


On some patient's skin types, the product takes longer to absorb, which sometimes resulted in pilling. But it still produced great results. 

Skin type: Dry, mature 
Benefits: Helps deeply hydrate, plump, and smooth the skin radicals 
Key ingredients: Hyaluronate, Glutamine 
Size: 1 oz / 30 mL 

❌  CONS 

  • Expensive 

✅  PROS 

  • Reduce and prevent fine lines and wrinkles 
  • Improve skin elasticity and firmness 
  • Lasts a long time 
  • Great  reviews 
VIEW ON AMAZON.COM

¹Ablon, Glynis. “Phototherapy with Light Emitting Diodes: Treating a Broad Range of Medical and Aesthetic Conditions in Dermatology.” The Journal of Clinical and Aesthetic Dermatology, Matrix Medical Communications, Feb. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC5843358/.

Lim SH, Sun Y, Thiruvallur madanagopal T, Rosa V, Kang L. Enhanced skin permeation of anti-wrinkle peptides via molecular modification. Sci Rep. 2018;8(1):1596. doi:10.1038/s41598-017-18454-z, https://www.nature.com/articles/s41598-017-18454-z

Mukherjee S, Date A, Patravale V, Korting HC, Roeder A, Weindl G. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clin Interv Aging. 2006;1(4):327-348. doi:10.2147/ciia.2006.1.4.327

© 2024 Skincare-productreviews.com. All Rights Reserved. 

Trademarks utilized on our website belong to their respective owners and no implied or endorsement of our website or services is intended.

Best Anti-Ageing Serums 2024 

Check Out Qure All-In-One Serum

Skin type: Combination, aging, sensitive
Benefits: Brightens skin tone, lightens dark spots and reduces fine lines
Key ingredients: Argireline® Peptide Solution, Niacinamide, Retinol, Hyaluronic Acid.
Size: 1 oz / 30 mL 

1.  Qure Skincare All-In-One Face Serum

A+ Rating

Tested & Recommended By World-Leading Dermatologists

"This will definitely work and there have been studies to show that this will definitely work to help your products penetrate better"

Dr Shah, MD (Doctorly)        Certified Dermatologist

"In terms of safety, the micro stamping devices, this [Qure's Micro-Infusion] is great..."

Dr Maxfield, MD (Doctorly)         Certified Dermatologist

“I personally think my products absorbed better, my skin looks a bit
brighter and that larger acne scar on my right cheek has started to fade after just TWO treatments!” 

Dr Mona Patel, MD         Certified Dermatologist

✅   PROS

  • Fades and prevents dark spots

  • Smooths fine lines and wrinkles

  • Contains great anti-aging ingredients

  • Well priced & affordable

  • Fragrance-free & vegan 

❌   CONS 

  • Not available in brick and mortar shops

  • Often sold out due to popularity 

The Bottom Line

Of all the serums that I’ve tested, this one blew me away!

Whenever I would recommend All-In-One Face Serum to my clients as part of their daily skincare routine - they'd always come back saying how their friends and husbands complimented them on their newfound plump and radiant skin.

It's anti-aging superpower secret? The high concentration of Argireline Peptides. Being the most trusted anti-aging peptide in the world, this 
ultimate wrinkle-fighting ingredient has been proven to prevent wrinkles from forming, stimulate collagen production and improve skin moisture levels. 

All of which particularly is needed as collagen gets broken down as we age, and with the ultimate goal having smoother, plumper, healthier skin.


This serum is an anti-ageing no-brainer.

It has the 
best quality ingredients for visible anti-aging results, at the lowest cost. It is also fragrance-free, vegan, and suitable for most skin types, and therefore takes my top spot! 

Check Out C E Ferulic Serum

The Bottom Line

This hardworking serum is very pricey, but is effective at improving signs of aging and photodamage to reduce the appearance of wrinkles while firming and brightening your complexion.


Enriched with high concentration of vitamin C, combined with ferulic acid and vitamin E, that work together to enhance skin's protection against environmental damage.


I like that this serum is fragrance-free but if you have sensitive skin then a patch test is recommended due to the high as some patients have reported reactions due to it high % of active ingredients.


It comes in at #2 instead of #1 because we saw the same (if not better) results as Qure’s All-In-One Face Serum with plumper, smoother and more radiant skin, but it’s nearly 3x the price. 

2.  SkinCeuticals C E Ferulic 

A- Rating 

Tested & Recommended By World-Leading Dermatologists

"This will definitely work and there have been studies to show that this will definitely work to help your products penetrate better"

Dr Shah, MD (Doctorly)        Certified Dermatologist

"In terms of safety, the micro stamping devices, this [Qure's Micro-Infusion] is great..."

Dr Maxfield, MD (Doctorly)         Certified Dermatologist

“I personally think my products absorbed better, my skin looks a bit
brighter and that larger acne scar on my right cheek has started to fade after just TWO treatments!” 

Dr Mona Patel, MD         Certified Dermatologist

✅   PROS

  • Fades and prevents dark spots

  • Smooths fine lines and wrinkles

  • Contains great anti-aging  ingredients

  • Well priced & affordable

  • Fragrance-free & vegan 

❌   CONS 

  • Not available in brick and mortar shops

  • Often sold out due to popularity 

✅   PROS

  • Improves skin texture and firmness

  • Helps minimize wrinkles

  • Fragrance free

❌   CONS 

  • Very pricey

  • Unpleasant smell

  • Some patients have reported problems with reactions

Skin type: Dry, mature
Benefits: Improves firmness and texture, protects skin from free radicals
Key ingredients: Vitamin C, ferulic acid
Size: 1 oz / 30 mL

Check Out A+ High-Dose Retinoid Serum

3.  Sunday Riley A+ High-Dose Retinoid Serum 

B+ Rating 

Tested & Recommended By World-Leading Dermatologists

"This will definitely work and there have been studies to show that this will definitely work to help your products penetrate better"

Dr Shah, MD (Doctorly)        Certified Dermatologist

"In terms of safety, the micro stamping devices, this [Qure's Micro-Infusion] is great..."

Dr Maxfield, MD (Doctorly)         Certified Dermatologist

“I personally think my products absorbed better, my skin looks a bit
brighter and that larger acne scar on my right cheek has started to fade after just TWO treatments!” 

Dr Mona Patel, MD         Certified Dermatologist

✅   PROS

  • Fades and prevents dark spots

  • Smooths fine lines and wrinkles

  • Contains great anti-aging  ingredients

  • Well priced & affordable

  • Fragrance-free & vegan 

❌   CONS 

  • Not available in brick and mortar shops

  • Often sold out due to popularity 

✅   PROS

  • Fades dark spots

  • Helps minimize wrinkles

  • Fragrance free

  • Improves congestion

  • Reduces fine lines

  • Available online and in certain high end retailers

❌   CONS 

  • Very pricey

  • Unpleasant smell

  • Some patients have reported problems with reactions

Skin type: Combination, oily, normal 
Benefits: Improve the look of lines and dark spots 
Key ingredients: Retinol 
Size: 1 oz / 30 mL 

The Bottom Line

This is not a retinol serum for first time retinol users as it’s a professional strength formula that consists of a 5% retinoid ester blend, 1% liposomal-encapsulated retinol, and blue-green algae to provide antioxidant protection. It also contains CoQ10 to help improve damaged or aging skin.


You’ll see instant gratification of a luminous complexion, but signs of aging are reduced over time.


However, due to its high strength concentration I wouldn’t recommend it for those with sensitive skin as the formula may be irritating and this is why it comes in at #3 spot.

Check Out Night Repair Complex

4.  Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex 

B- Rating 

Tested & Recommended By World-Leading Dermatologists

"This will definitely work and there have been studies to show that this will definitely work to help your products penetrate better"

Dr Shah, MD (Doctorly)        Certified Dermatologist

"In terms of safety, the micro stamping devices, this [Qure's Micro-Infusion] is great..."

Dr Maxfield, MD (Doctorly)         Certified Dermatologist

“I personally think my products absorbed better, my skin looks a bit
brighter and that larger acne scar on my right cheek has started to fade after just TWO treatments!” 

Dr Mona Patel, MD         Certified Dermatologist

✅   PROS

  • Fades and prevents dark spots

  • Smooths fine lines and wrinkles

  • Contains great anti-aging  ingredients

  • Well priced & affordable

  • Fragrance-free & vegan 

❌   CONS 

  • Not available in brick and mortar shops

  • Often sold out due to popularity 

✅   PROS

  • Keeps skin hydrated

  • Softens fine lines 

  • Won’t clog pores

❌   CONS 

  • Runs out quickly 

  • Pricey for what it is

  • Not enough active ingredients 

Skin type: Dry, sensitive
Benefits: Locks in hydration and softens skin  
Key ingredients: Sodium hyaluronate (a form of hyaluronic acid) 
Size: 1 oz / 30 mL 

The Bottom Line

This serum has humectants, emollients, probiotics, soothing botanicals, and a peptide, to address signs of aging caused by the environmental assaults of modern life — like pollution, blue light, and environmental toxins.


It has a good blend of hydrating and soothing ingredients to help increase skin’s hydration.


This serum comes in at my #4 spot as it lacks active ingredients that are proven to correct signs of aging and we did not see the same results as Qure All-In-One Face Serum.

Qure Skincare All-In-One Face Serum

Skin type: Combination, aging, sensitive
Benefits: Brightens skin tone, lightens dark spots and reduces fine lines
Key ingredients: Argireline® Peptide Solution, Niacinamide, Retinol, Hyaluronic Acid.
Size: 1 oz / 30 mL

1.

A+ Rating

Tested & Recommended By World-Leading Dermatologists

This will definitely work
and there have been
studies to show that this will definitely work to help your products penetrate better"

Dr Shah, MD (Doctorly)
Certified Dermatologist

"In terms of safety, the micro stamping devices, this [Qure's Micro-Infusion] is great..."

Dr Maxfield, MD (Doctorly)
Certified Dermatologist

“I personally think my
products absorbed better, my skin looks a bit brighter and that larger acne scar on my right cheek has started to fade after just TWO treatments!” 

Dr Mona Patel, MD
Certified Dermatologist

VIEW ON QURESKINCARE.COM

✅  PROS 

  • Fades and prevents dark spots
  • Smooths fine lines and wrinkles
  • Contains great anti-aging  ingredients
  • Well priced & affordable
  • Fragrance-free & vegan

❌  CONS 

  • Not available in brick and mortar shops
  • Often sold out due to popularity 

The Bottom Line

Of all the serums that I’ve tested, this one blew me away!

Whenever I would recommend All-In-One Face Serum to my clients as part of their daily skincare routine - they'd always come back saying how their friends and husbands complimented them on their newfound plump and radiant skin.

It's anti-aging superpower secret? The high concentration of Argireline Peptides. Being the most trusted anti-aging peptide in the world, this
ultimate wrinkle-fighting ingredient has been proven to prevent wrinkles from forming, stimulate collagen production and improve skin moisture levels.  

All of which particularly is needed as collagen gets broken down as we age, and with the ultimate goal having smoother, plumper, healthier skin.

This serum is an anti-ageing no-brainer.

It has the
best quality ingredients for visible anti-aging results, at the lowest cost. It is also fragrance-free, vegan, and suitable for most skin types, and therefore takes my top spot! 

Best Anti-Ageing Serums 2024 

SkinCeuticals C E Ferulic 

2.

A- Rating 

Tested & Recommended By World-Leading Dermatologists

This will definitely work
and there have been
studies to show that this will definitely work to help your products penetrate better"

Dr Shah, MD (Doctorly)
Certified Dermatologist

"In terms of safety, the micro stamping devices, this [Qure's Micro-Infusion] is great..."

Dr Maxfield, MD (Doctorly)
Certified Dermatologist

“I personally think my
products absorbed better, my skin looks a bit brighter and that larger acne scar on my right cheek has started to fade after just TWO treatments!” 

Dr Mona Patel, MD
Certified Dermatologist

VIEW ON DERMASTORE.COM

✅  PROS 

  • Improves skin texture and firmness 
  • Helps minimize wrinkles 
  • Fragrance free

❌  CONS 

  • Very pricey
  • Unpleasant smell
  • Some patients have reported problems with reactions 

Skin type: Dry, mature 
Benefits: Improves firmness and texture, protects skin from free radicals 
Key ingredients: Vitamin C, ferulic acid 
Size: 1 oz / 30 mL

The Bottom Line

This hardworking serum is very pricey, but is effective at improving signs of aging and photodamage to reduce the appearance of wrinkles while firming and brightening your complexion.


Enriched with high concentration of vitamin C, combined with ferulic acid and vitamin E, that work together to enhance skin's protection against environmental damage.


I like that this serum is fragrance-free but if you have sensitive skin then a patch test is recommended due to the high as some patients have reported reactions due to it high % of active ingredients.


It comes in at #2 instead of #1 because we saw the same (if not better) results as Qure’s All-In-One Face Serum with plumper, smoother and more radiant skin, but it’s nearly 3x the price. 

VIEW ON QURESKINCARE.COM

Sunday Riley A+ High-Dose Retinoid Serum 

3.

B+ Rating 

Tested & Recommended By World-Leading Dermatologists

This will definitely work
and there have been
studies to show that this will definitely work to help your products penetrate better"

Dr Shah, MD (Doctorly)
Certified Dermatologist

"In terms of safety, the micro stamping devices, this [Qure's Micro-Infusion] is great..."

Dr Maxfield, MD (Doctorly)
Certified Dermatologist

“I personally think my
products absorbed better, my skin looks a bit brighter and that larger acne scar on my right cheek has started to fade after just TWO treatments!” 

Dr Mona Patel, MD
Certified Dermatologist

The Bottom Line

This is not a retinol serum for first time retinol users as it’s a professional strength formula that consists of a 5% retinoid ester blend, 1% liposomal-encapsulated retinol, and blue-green algae to provide antioxidant protection. It also contains CoQ10 to help improve damaged or aging skin.


You’ll see instant gratification of a luminous complexion, but signs of aging are reduced over time.


However, due to its high strength concentration I wouldn’t recommend it for those with sensitive skin as the formula may be irritating and this is why it comes in at #3 spot. 

Skin type: Combination, oily, normal  
Benefits: Improve the look of lines and dark spots 
Key ingredients: Retinol 
Size: 1 oz / 30 mL 

❌  CONS 

  • Skin needs to build a tolerance 
  • Not suitable for all skin types 
  • Only features one main active ingredient for anti-aging 

✅  PROS 

  • Fades dark spots 
  • Can layer with other serums 
  • Improves congestion 
  • Reduces fine lines 
  • Available online and in certain high end retailers 
VIEW ON SUNDAYRILEY.COM

Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex 

4.

B- Rating 

Tested & Recommended By World-Leading Dermatologists

This will definitely work
and there have been
studies to show that this will definitely work to help your products penetrate better"

Dr Shah, MD (Doctorly)
Certified Dermatologist

"In terms of safety, the micro stamping devices, this [Qure's Micro-Infusion] is great..."

Dr Maxfield, MD (Doctorly)
Certified Dermatologist

“I personally think my
products absorbed better, my skin looks a bit brighter and that larger acne scar on my right cheek has started to fade after just TWO treatments!” 

Dr Mona Patel, MD
Certified Dermatologist

VIEW ON SEPHORA.COM

✅  PROS 

  • Keeps skin hydrated 
  • Softens fine lines 
  • Won’t clog pores 

❌  CONS 

  • Runs out quickly 
  • Pricey for what it is 
  • Not enough active ingredients 

Skin type: Dry, sensitive 
Benefits: Locks in hydration and softens skin 
Key ingredients: Sodium hyaluronate (a form of hyaluronic acid) 
Size: 1 oz / 30 mL 

The Bottom Line

This serum has humectants, emollients, probiotics, soothing botanicals, and a peptide, to address signs of aging caused by the environmental assaults of modern life — like pollution, blue light, and environmental toxins.


It has a good blend of hydrating and soothing ingredients to help increase skin’s hydration.


This serum comes in at my #4 spot as it lacks active ingredients that are proven to correct signs of aging and we did not see the same results as Qure All-In-One Face Serum. 

Countless patients have come to me over the years complaining of crow’s feet, dull skin, fine lines, and more. Many of them are convinced that their only hope for smooth, youthful-looking skin is to go under the needle.

However, one of the best ways to combat signs of aging is by using anti-aging skincare. This is one of the most effective, non-invasive ways to address signs of aging like wrinkles and fine lines, hyperpigmentation, hydration, sagging skin and more.

But the biggest problem for my patients is that the market is absolutely flooded with competition, and the cosmetics industry is not only hugely profitable, but growing.

Hundreds and hundreds of different products all claiming to do the same thing can't be equally worth your time or money, so 
how do you figure out which one to buy?

With so many products on the market, it seems an impossible task to sort the good from the bad, the nice-smelling but useless serums from the effective “holy grail” skincare.

Over the years I have had the opportunity to test hundreds of anti-aging serums on both myself and my patients. And there have been a few standout winners that I keep coming back to.

Today, I would like to share with you my top 5 serums for smooth, youthful-looking skin to enhance the natural beauty of your face…

by Qure Skincare

872 Reviews

Qure All-In-One Face Serum

Contains active & clinically-proven ingredients that brightens skin tone, lightens dark spots and reduces appearance of fine lines.  

2,367 people chose this today

Before $85.00  NOW $59.00

CLICK TO SHOP NOW

   

High concentration of Argireline Peptides that leading Dermatologists
recommend as a topical option to mimic Botox.

Affordable price compared to other serums with peptides and retinol formula.

Fast shipping to USA, Canada, United Kingdom and Australia.

Suitable for all skin types.

Best Overall

As the years go by, our skin starts to look worse than it used to.

Due to natural processes, depletion of collagen and environmental factors, wrinkles and other unsightly things on our skin can make us look old and tired – sometimes older than we really are.

Collagen provides the support matrix/mattress underpinning healthy skin and is a key determinant to the preservation of skin firmness and elasticity [1,2]. Type I is the main collagen found in skin, representing 80%-90% of skin collagen.

Collagen is key for preservation of skin firmness and elasticity, and making our skin look youthful. With age, the ability to replenish collagen naturally decreases by about 1.0%-1.5% per year.

CITATIONS